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After a heart attack, multiple drugs can affect quality of life

Written by Jonathan Block

Elderly nursing home patients prescribed a multitude of medications following a heart attack may live longer compared to those given just one prescription drug, but it can come at a cost: It may negatively impact their quality of life.

Researchers examined claims data from nearly 4,800 nursing home residents, most of whom were white women with an average age of 84. The study looked at deaths, hospitalizations and decreased ability to manage daily activities after the residents were prescribed one of four kinds of medications after leaving the hospital following a heart attack. Those medications were beta blockers, blood thinners, blood pressure drugs and statins.

Results, published in Circulation: Cardiovascular Quality and Outcomes, showed that residents prescribed three or four medications after hospital discharge were less likely to die within 90 days compared with those prescribed just one medication. The death risk between those taking one or two prescription drugs did not differ.

Additional analysis found that, with the exception of blood thinners, greater prescription drug use was associated with a 30% increase in functional decline.

“Since using more medications may interfere with older adults’ ability to do their daily activities, more medications should not be taken by older adults who wish to maintain their independence and daily functioning rather than live longer,” lead author Andrew R. Zullo, PharmD, PhD, an assistant professor at the Brown University School of Public Health, said in a statement. “Using more medications after a heart attack does not simply improve all health outcomes.”

This article originally appeared in Medshadow.org

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